促销 γ-Tubulin Antibody
开学季,购买CST信号通路抗体,精美礼品送不停! 查看详情>
货号: 5886S 品牌: CST 反应种属:
Human/Mouse/Rat/Monkey
Human/Mouse/Rat/Monkey
应用:
W
W
规格: 100ul
产品说明书
分享:

价格: ¥ 3400.00

目录价: ¥3400.00

数量
- +
加入购物车
产品介绍商品评论
概述
反应种属
Human/Mouse/Rat/Monkey
来源宿主
Rabbit
应用
W
目标/特异性
γ-Tubulin Antibody recognizes endogenous levels of total γ-tubulin protein.
使用方法
WB(1:1000)
是否允许进口
允许
是否危险品
非危险品
性能
供应商
CST
灵敏度
Endogenous
背景

Globular tubulin subunits comprise the microtubule building block, with α/β-tubulin heterodimers forming the tubulin subunit common to all eukaryotic cells. As a critical part of the microtubule-organizing center (MTOC), the third member of the tubulin superfamily, γ-tubulin, is required for microtubule nucleation as well as centrosome duplication and spindle assembly (1,2, reviewed in 3). γ-tubulin forms complexes of two different sizes: γ-tubulin small complex (γ-TuSC) and the larger γ-tubulin ring complex (γ-TuRC). Each complex consists of a number of γ-tubulin complex proteins (GCPs) with γ-tubulin itself being considered GCP1. GCP2-6 all share sequence similarity in 5 different regions and it is thought that these areas could play a role in the proper folding of the proteins (4). γ-TuSC is composed of two γ-tubulin molecules as well as GCP2 and GCP3. γ-TuRC is made up of a ring of multiple copies of γ-TuSC in addition to GCP4, 5, and 6. Another protein, GCP-WD/NEDD1, which lacks sequence similarity with the other GCPs, associates with the γ-TuRC. GCP-WD/NEDD1 has been shown to regulate localization of the γ-TuSC to spindles and centrosomes (5-8). In mammals, phosphorylation of γ-tubulin at Ser131 by SADB controls the activity of the γ-TuRC. The hypothesis is that this phosphorylation stabilizes the protein in a conformation that stimulates centrosome amplification (9).

存放说明
-20C
计算分子量
50

参考图片

Western blot analysis of extracts from various cell lines using γ-Tubulin Antibody.Western blot analysis of extracts from various cell lines using γ-Tubulin Antibody.

使用γ-Tubulin Antibody,免疫印迹(Western Blot)分析不同细胞中γ-Tubulin。

声明 :本官网所有报价均为常温或者蓝冰运输价格,如有产品需要干冰运输,需另外加收干冰运输费。